Abstract: Presented is a life prediction model based on the variation of electrical resistance for metallic components experiencing high cycle fatigue load. Combining nonlinear continual fatigue damage accumulation theories with calculation formula for electrical resistance of metals, and taking into account the nonlinear effects of cycle stress on damage accumulation, a promising damage measuring method and a fatigue life prediction model concerned only with variation of electrical resistance are then proposed. The effect of cycle stress on nonlinear damage factor is analyzed as well. Experimental data from 45# steel agree well with the theoretical results adopting the proposed model in this paper.