Abstract: In order to reduce the workload and construction period of spherical tank non-destructive testing, the practice showed that the overall detection method with 192Ir and T2 class film could be used in nondestructive testing of low temperature spherical tank, and film blackness and the sensitivity of image quality met standard requirements. The method had the advantage of short construction period, quality, and HSE management over the traditional X-ray detection. It was also a successful application case of requirements on the γ-ray detection in the new version of JB/T 4730—2005 “non-destructive testing of pressure equipment”.