Abstract: A sort of fatigue life prediction method for analyzing material was studied and improved based on industry CT images. First, crackle initiation and extending courses are divided into micro scale thinness sight crackle, CT scale crackle and macroscopic crackle; Second, different crackle initiation and extending standards are adopted to calculate material fatigue life; Finally, the fatigue life of the material is achieved by adding each phase fatigue life. Compared to fatigue cumulative damage theory method and nominal stress method etc, the high precision of the fatigue life for the material was got better by this method.