Abstract: Phased array full-focus imaging is a cutting-edge technology in the field of nondestructive testing, and the composite mode full-focus technology is currently the focus of research. This detection technology can integrate defect information from different angles into a single full-focus image, significantly improving the reconstruction ability for unknown defects. However, as the number of fusion modes increases, noise and structural artifacts are inevitably introduced, seriously affecting the evaluation of detection results.To address the interference of superimposed noise and artifacts in composite mode full-focus imaging, this paper proposed a full-focus multi-mode adaptive regional fusion method that utilized the physical information of TT mode direct views to accurately locate defect positions and perform targeted regional fusion. Experimental results showed that the adaptive regional fusion method effectively filtered out the interference of structural artifacts while ensuring imaging accuracy, with an average improvement of contrast-to-noise ratio (CNR) by approximately 34.06%.